◆ 主要学习工作经历

●2007.9 – 2011.6: B.Sc. in Chinese Herbal Medicines, Shandong Agricultural University, Tai’an, China.

●2011.9 – 2014.6: M.Sc. in Chemistry of Chinese Herbal Medicines, China Pharmaceutical University, Nanjing, China.

●2014.9 – 2018.6: Ph.D. in Biotechnology and Chemical Engineering, Nanjing University of Science and Technology, Nanjing, China.

●2023.12 – 2025.1: Visiting Researcher, Medizinische Hochschule Hannover (Hannover Medical School), Hannover, Germany.

●2018.7 – Present: Faculty in College of Life Sciences, Anhui Normal University, Wuhu, China.

◆ 主要社会兼职

●Member, Chinese Society for Cell Biology

●Council Member, Anhui Society of Anatomy

●Young Editorial Board Member, Chinese Herbal Medicines

◆ 主要研究内容

Cellular Metabolic Regulation, Functional Metabolomics, Target Discovery, and Functional Validation in Metabolic Diseases.

Pharmacological Mechanisms of Chinese Herbal Medicines and Natural Products in Preventing and Treating Major Metabolic Diseases.

◆ 主要研究课题

1. Natural Science Foundation of China (82405142), 2025-2027, Principal Investigator

2. Natural Science Foundation of Anhui Province (1908085QH342), 2019-2021, Principal Investigator

3. Open Project of Guangxi Key Laboratory of Precision Medicine in Cardio-Cerebrovascular Diseases Control and Prevention, GXXNXG202102, 2021-2023, Principal Investigator

◆ 主要研究成果

一、代表性论文及论著：

Zhou H^#, Sun DD^#, Wang DM, Zhu ZR, Hong XL, Fang R, Wang H, Li MH*, Deciphering Metabolic Responses in Traumatic Brain Injury Patients with Different Severity Using ¹H NMR-Based Serum Metabolomics, Scientifica. 2025: 5522830.

Li MH^#, Meng YY^#, Hong XL, Chai H, Huang JY, Wang FG, Zhang WJ, Wang JC, Liu QW*, Xu Y^*. Anti-atherosclerotic effect of tetrahydroxy stilbene glucoside via dual-targeting of hepatic lipid metabolisms and aortic M2 macrophage polarization in ApoE^-/- mice. J Pharm Biomed Anal. 2024, 248: 116338.

Li MH^#, Lu W^#, Meng YY, Zhang WJ, Wang FG, Sun L, Xu Y^*. Tetrahydroxy Stilbene Glucoside Alleviates Ischemic Stroke by Regulating Conformation-Dependent Intracellular Distribution of PKM2 for M2 Macrophage Polarization. J Agric Food Chem. 2022, 70(49): 15449-15463.

Li MH^#, Feng X^#, Deng Ba DJ, Chen C, Ruan LY, Xing YX, Chen LY, Zhong GJ*, Wang JS*. Hepatoprotection of Herpetospermum caudigerum Wall. against CCl₄-induced liver fibrosis on rats. J Ethnopharmacol. 2019, 229: 1-14.

Li MH, Ruan LY, Chen C, Xing YX, Hong W, Du RH, Wang JS*. Protective effects of Polygonum multiflorum on ischemic stroke rat model analysed by ¹H NMR metabolic profiling. J Pharm Biomed Anal. 2018, 155: 91-103.

Li MH^#, Du HZ^#, Kong GJ, Liu LB, Li XX, Lin SS, Jia AQ, Yuan ST*, Sun L*, Wang JS*. Nuclear Magnetic Resonance-Based Metabolomics Approach to Evaluate the Prevention Effect of Camellia nitidissima Chi on Colitis-Associated Carcinogenesis. Front Pharmacol. 2017, 8: 447.

Li MH, Ruan LY, Zhou JW, Fu YH, Jiang L, Zhao H, Wang JS*. Metabolic profiling of goldfish (Carassius auratis) after long-term glyphosate-based herbicide exposure. Aquat Toxicol. 2017, 188: 159-169.

Li MH, Xu HD, Liu Y, Chen T, Jiang L, Fu YH, Wang JS*. Multi-tissue metabolic responses of goldfish (Carassius auratus) exposed to glyphosate-based herbicide. Toxicol Res (Camb). 2016, 5(4): 1039-1052.

Li MH^#, Ruan LY^#, Liu Y, Xu HD, Chen T, Fu YH, Jiang L, Wang JS*. Insight into biological system responses in goldfish (Carassius auratus) to multiple doses of avermectin exposure by integrated ¹H NMR-based metabolomics. Toxicol Res. 2015, 4(5), 1374-1388.

Li MH, Wang JS*, Lu ZG, Wei DD, Yang MH, Kong LY*. NMR-based metabolomics approach to study the toxicity of lambda-cyhalothrin to goldfish (Carassius auratus). Aquat Toxicol. 2014, 146: 82-92.

Li TX, Liang JX, Liu LL, Shi FC, Jia XW, Li MH*, Xu CP*. Novel kojic acid derivatives with anti-inflammatory effects from Aspergillus versicolor. Fitoterapia. 2021, 154: 105027.

Yang L^#, Li MH^#, Shen M, Bu S, Zhu B, He F, Zhang XP, Gao X*, Xiao JX*. Chromosome-level genome assembly and annotation of the native Chinese wild blueberry Vaccinium bracteatum. Fruit Res. 2022, 2(1), 1-14.

Ruan LY^#, Li MH^#, Xing YX, Hong W, Chen C, Chen JF, Xu H, Zhao WL, Wang JS*. Hepatotoxicity and hepatoprotection of Polygonum multiflorum Thund. as two sides of the same biological coin. J Ethnopharmacol. 2019, 230: 81-94.

Feng X^#, Li MH^#, Xia J, Deng Ba DJ, Ruan LY, Xing YX, Chen C, Wang JS*, Zhong GJ*. Tibetan Medical Formula Shi-Wei-Gan-Ning-Pill Protects Against Carbon Tetrachloride-Induced Liver Fibrosis - An NMR-Based Metabolic Profiling. Front Pharmacol. 2018, 9: 965.

Xing YX^#, Li MH^#, Tao L, Ruan LY, Hong W, Chen C, Zhao WL, Xu H, Chen JF, Wang JS*. Anti-Cancer Effects of Emodin on HepG2 Cells as Revealed by ¹H NMR Based Metabolic Profiling. J Proteome Res. 2018, 17(5): 1943-1952.

Lu ZG^#, Li MH^#, Wang JS*, Wei DD, Liu QW, Kong LY*. Developmental toxicity and neurotoxicity of two matrine-type alkaloids, matrine and sophocarpine, in zebrafish (Danio rerio) embryos/larvae. Reprod Toxicol. 2014, 47: 33-41.

李明会, 阮玲玉, 赵文龙, 孟辉辉, 汪俊松*. 基于代谢组学/药动学整合策略的多组分中药药效物质基础研究. 世界科学技术-中医药现代化. 2018, 8: 1471-1475.

Highly motivated candidates with a genuine passion for scientific research are warmly encouraged to join our lab!